Dr. Payton-Stewart's research focuses on identifying novel therapeutics for cancer through the incorporation two discrete disciplines, synthetic chemistry and molecular biology. The Payton-Stewart research projects involves the design, synthesis, characterization, and biological screening of novel anti-cancer agents. The research further involves understanding the molecular mechanism and biological activity of naturally occurring plant phytoalexins and their analogs as they pertain to breast carcinomas. One major focus of the Payton-Stewart research laboratory is to identify the structural activity relationship (SAR) of synthesize analogs. This research laboratory designs anti-cancer agents for various forms of cancer such prostate, triple negative breast cancer, endocrine resistant breast and prostate cancer.
