In the Fuchs lab we want to know how the composition of a protein dictates both its structure and its function. This interest runs the gamut of protein chemistry from understanding the biology of very simple, repetitive peptide sequences to dissecting the interactions of large protein complexes.
Currently our research is focused on two main areas - Post-translational modifications (PTMs) of proteins and the biology of repetitive protein domains. We emphasize creative thinking and cross-disciplinary approaches to answer questions regarding protein structure and function. We employ a broad spectrum of tools and systems from fluorescence microscopy, chemical synthesis, and biophysical methods to classical yeast genetics and mammalian cell culture
