Cross-regulation of cellular function at the host-Giardia interface. We are studying the molecular mechanisms underlying the intestinal disturbances as well as the bases for symptoms variability and severity associated with Giardia lamblia infections.
Protein trafficking and import to the Giardia's mitosome. Using an overexpression system we are cloning and expressing human mitochondria and parasite genes in the Giardia to understand the level of conservation and divergence of the mitosomal protein import system.
Mechanims of signal transduction and protein regulation in Giardia lamblia Evolution of eukaryotic parasite and other Diplomonadida.
