The research interest in our lab is the regulation of blood pressure and cardiovascular diseases in central nervous system. The renin-angiotensin system (RAS) has been shown to play an important role in blood pressure regulation and cardiovascular function. Our main focus is on the physiological and pathophysiological role of various new RAS components in disease models and their signaling pathways, and to improve the treatment of hypertension and other CV diseases. We use physiological genomics approaches, linking gene to function by using transgenic and knockout mice models. Using our expertise in continuous BP recordings using radio telemetric system and analysis of autonomic function combined to molecular biology, physiological, and pharmacological tools to investigate the role of these new components of the RAS on regulation of BP and cardiovascular diseases.
