The research questions we are trying to answer are revolving around "How do malaria parasites survive in the host?", "What is are the mechanisms of sexual differentiation?", and "What special roles do lipids play in the life-cycle progression of the malaria parasite?". Hence the Maier lab focussed on the identification of molecules involved in malaria pathogenesis and transmission. In order to elucidate the functions of these molecules we use biochemical, molecular and cell biological techniques. The long-term goal is not only to identify and develop new intervention strategies against malaria, but also to understand the underlying biological principles.