To increase our understanding of biology and medicine, the scientific community requires the continued development of new technologies for studying and manipulating cell physiology. The research interests of the Dore Laboratory at NYUAD lie at the interface of chemistry and biology, creating new technology to study complex biological systems. The power to design and synthesize molecules with appropriate function coupled with an understanding of reaction mechanisms enables the work. The research is multidisciplinary in nature, involving organic chemistry, biochemistry, photochemistry, microscopy, and molecular and cell biology. The complexity of the problems addressed necessitates collaborations with other scientists around the world. Current projects focus on three major areas:
Light-driven tools to study biological systems
CaaX proteases and the role they play in regulating cell physiology
Discovering inhibitors of sodium-glucose cotransporters SGLT1 and SGLT2
