The Pravetoni lab at the University of Minnesota Medical School is seeking a scientist for development of vaccines and antibody-based therapeutics to counteract opioid use disorders and overdoses. Our unique multidisciplinary research program integrates rational vaccine design, immunomodulators, formulation/delivery platforms, pre-clinical models, analysis of B and T cell lymphocyte repertoire, GLP/GMP studies to support regulatory approval and clinical evaluation, and ad hoc industry collaborations. Our team is currently planning Phase I clinical trials of vaccines targeting various opioids. Strategies and platforms will be applied to development of vaccines or antibodies against biological or chemical threats. We are seeking a scientist to qualify vaccine and monoclonal antibody (mAb) lots by various assays including ELISA, BCA assay, Protein G chromatography, LAL assay for endotoxin content, SDS-PAGE. Additional tasks will involve coupling chemistry to generate conjugate vaccines, and their purification by standard methods. Protein expression or antibody purification experience is highly desired. For our recent publications search PubMed for "Pravetoni M". Check us out at our lab website: http://pharmnas-2165-jh.ahc.umn.edu/~ad%5Cshoem054/
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Cheryl Marker Schmidt Pharmacology University of Minnesota, Twin Cities 3-250A Nils Hasselmo Hall 312 Church Street SE