Assistant Project Scientist Immunology Cox Lab - Molecular and Cellular Biology

Position overview Position title: Assistant Project Scientist
Salary range: The UC academic salary scales set the minimum pay determined by rank and step at appointment. See the following table(s) for the current salary scale(s) for this position: https://www.ucop.edu/academic-personnel-programs/_files/2023-24/july-2023-acad-salary-scales/t37-b.pdf. A reasonable estimate for this position is $75,300-$82,900.

Percent time: 100%

Anticipated start: Summer 2024

Position duration: One year with the possibility of extension based on performance and availability of funding.

Application Window
Open date: April 8, 2024

Most recent review date: Monday, Apr 22, 2024 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Wednesday, May 8, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

The department of Molecular and Cellular Biology at the University of California, Berkeley seeks applications for an Assistant Project Scientist in the Cox Lab, in the area of Immune responses to Mycobacterium tuberculosis infection.

The Cox lab studies the interactions between the important human pathogen Mycobacterium tuberculosis, the etiological agent of tuberculosis, and the mammalian immune system. We apply both bacterial host genetic techniques to uncover new pathways that underlie pathogenesis and protective responses of the host.

The TBRU project is a highly collaborative effort consisting of a team of researchers located at UC Berkeley and partners around the world focusing on leveraging the variations in infection outcomes in humans to identify the host and bacterial genetic factors that underlie these phenomena.

The Assistant Project Scientist will develop a pipeline to utilize new CRIPSR-based genetic tools to perform high-throughput genetic screens to identify murine macrophage genes that modulate inflammatory responses during M. tuberculosis infection. Key objectives include the development of new methods that will allow for in vivo screening of genetic perturbations in an aerosol model of infection. The incumbent will participate with our partners studying human genetic susceptibility to infection to devise new mouse models to understand complex phenomena, including dissemination to the brain and resistance to initial infection. A key factor will be using computational approaches to identify pathways from large, complex datasets from human genetic studies to inform selection of genetic targets in mice.

The incumbent will participate in background research, the analysis and interpretation of results; will prepare written and oral summary reports [internal and external]. The incumbent will also help to advise a group of junior researchers, and reporting. The incumbent will attend and actively support scientific seminars, workshops, working team meetings and other venues for presentations of results and will develop and maintain collaborative research relationships; will pursue publication of research in peer-reviewed journals; and may pursue additional funding opportunities consistent with existing and future research programs and goals.

This position provides full benefits.

Lab: https://www.coxlab.berkeley.edu/

Contract: https://ucnet.universityofcalifornia.edu/labor/bargaining-units/ra/contract.html

Qualifications
Basic qualifications (required at time of application)
PhD (or equivalent international degree)

Additional qualifications (required at time of start)
Four years of post-degree research experience by start date
Publication record in peer reviewed journals

Preferred qualifications
PhD in Immunology
Extensive experience using sophisticated cell-based immunological assays including flow cytometry, cell sorting, high-density cell imaging, single-cell sequencing, to study infection in mice
Experience using CRISPR-based genetic tools to manipulate immune cells, especially macrophages, and perform forward genetic screening
Experience working with BSL3-level pathogens and using mouse models of infection, including adoptive transfer experiments
The ideal candidate is able to develop and troubleshoot new theoretical ideas and is enthusiastic about pursuing exciting and fundamental evolutionary theoretical questions

Application Requirements

Document requirements

• Curriculum Vitae - Your most recently updated C.V.
• Cover Letter
• Statement of Research
• Statement on Contributions to Advancing Diversity, Equity, and Inclusion - Statement on your contributions to diversity, equity, and inclusion, including information about your understanding of these topics, your record of activities to date, and your specific plans and goals for advancing equity and inclusion if hired at Berkeley. More Information and guidelines.

Reference requirements

• 3-5 required (contact information only)

Apply link: https://aprecruit.berkeley.edu/JPF04344

Help contact: jeff.cox@berkeley.edu

About UC Berkeley

UC Berkeley is committed to diversity, equity, inclusion, and belonging. The excellence of the institution requires an environment in which the diverse community of faculty, students, and staff are welcome and included. Successful candidates will demonstrate knowledge and skill related to ensuring equity and inclusion in the activities of their academic position (e.g., teaching, research, and service, as applicable).

The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct

In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

Job location
Berkeley, CA


To apply, visit https://aprecruit.berkeley.edu/JPF04344