Job ID: 103273

Post Doctoral Scientist - Microbial Pathogenesis

Nationwide Children's Hospital/Ohio State University

  • Feb. 5, 2018
  • Post Doctoral Scientist - Microbial Pathogenesis
  • Microbial Pathogenesis
  • Nationwide Children's Hospital/Ohio State University
    Columbus, OH
  • Open until Filled
  • Available Immediately
  • Post-Doc
  • Biology - Microbiology
    Biology - Biochemistry

The Center for Microbial Pathogenesis within the Research Institute at Nationwide Children’s Hospital is seeking a Postdoctoral Scientist to study the role of the nontypeable Haemophilus influenzae phasevarion in pathogenesis of otitis media and other diseases of the respiratory tract. To be considered, the candidate must have a Ph.D. in bacterial molecular biology, microbiology, immunology or biochemistry. Experience in bacterial molecular biology is required. Applicants with an interest in the molecular mechanisms that underlie polymicrobial (viral-bacterial) diseases, the contributions of biofilms to the pathogenesis of diseases of the airway, and the immune response to these diseases are encouraged to apply. The Postdoctoral Scientist will investigate the phasevarion of nontypeable Haemophilus influenzae as part of a funded grant from the NIH/NIDCD, with the goal of becoming independent in his/her research effort. Applicants must be comfortable and willing to work with animal models of disease. The Postdoctoral Scientist will also be responsible for the supervision of technicians and student trainees and ultimately procurement of external research funding.

  • Excellent communication skills
  • Demonstrated peer-reviewed publication record
  • Experience in preparation of abstracts and scientific presentations
  • Strong mathematical and analytical skills
  • Experience in molecular cloning and generation of bacterial mutants
  • Working knowledge of bacterial regulation and hands-on experience in the study of gene and protein expression
  • Bacterial & eukaryotic DNA, RNA and protein isolation
  • Experience with animal models of disease
  • Primary cell culture
  • Proficiency in immunological assessments (i.e. ELISA, flow cytometry) and histology
  • Ability to be productive independently as well as a part of the laboratory team
  • Must be able to occasionally work after hours and/or weekends for experiments
    Please review these peer-reviewed publications regarding this project:
  • Brockman KL, et al. Sci Rep. 2017 Jun 9;7(1):3161. PMID: 28600561
  • Brockman KL, et al. J Infect Dis. 2016 Sep 1;214(5):817-24. PMID: 27288538
  • Atack JM, et al. Nat Commun. 2015 Jul 28;6:7828. PMID: 26215614
    Nationwide Children’s Hospital is an equal opportunity employer that values diversity. Candidates of diverse backgrounds are encouraged to apply. Interested candidates should submit a letter describing experience, CV, and 3 reference letters to Dr. Lauren O. Bakaletz.

  • EOE M/F/Disability/Vet

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